In this chapter, an application of a neuromorphic controller is proposed for hazard mitigation of smart structures under seismic excitations. The new control system is developed through the integration of a brain emotional learning-based intelligent control (BELBIC) algorithm with a proportional-integral-derivative (PID) compensator and a clipped algorithm. The BELBIC control is based on the neurologically inspired computational model of the amygdala and the orbitofrontal cortex. A building structure employing a magnetorheological (MR) damper under seismic excitations is investigated to demonstrate the effectiveness of the proposed hybrid clipped BELBIC-PID control algorithm. The performance of the proposed hybrid neuromorphic controller is compared with the one of a variety of conventional controllers such as a passive, PID, linear quadratic Gaussian (LQG), and emotional control systems. It is shown that the proposed hybrid neuromorphic controller is effective in improving the dynamic responses of structure-MR damper systems under seismic excitations, compared to the benchmark controllers.