Epithelial Cancer Detection by Oblique-Incidence Optical Spectroscopy Conference Paper uri icon


  • This paper presents a study on non-invasive detection of two common epithelial cancers (skin and esophagus) based on oblique incidence diffuse reflectance spectroscopy (OIDRS). An OIDRS measurement system, which combines fiber optics and MEMS technologies, was developed. In our pilot studies, a total number of 137 cases have been measured in-vivo for skin cancer detection and a total number of 20 biopsy samples have been measured ex-vivo for esophageal cancer detection. To automatically differentiate the cancerous cases from benign ones, a statistical software classification program was also developed. An overall classification accuracy of 90% and 100% has been achieved for skin and esophageal cancer classification, respectively. 2009 SPIE.

name of conference

  • Advanced Biomedical and Clinical Diagnostic Systems VII

published proceedings


author list (cited authors)

  • Garcia-Uribe, A., Balareddy, K. C., Zou, J., Wang, K. K., Duvic, M., & Wang, L. V.

citation count

  • 2

complete list of authors

  • Garcia-Uribe, Alejandro||Balareddy, Karthik C||Zou, Jun||Wang, Kenneth K||Duvic, Madeleine||Wang, Lihong V

editor list (cited editors)

  • Mahadevan-Jansen, A., Vo-Dinh, T., & Grundfest, W. S.

publication date

  • February 2009