Oblique-Incidence Spatially Resolved Diffuse Reflectance Spectroscopic Diagnosis of Skin Cancer Conference Paper uri icon


  • This paper presents the use of spatially resolved oblique-incidence diffuse reflectance spectroscopy for skin cancer diagnosis. Spatio-spectral data from 166 pigmented skin lesions were collected for the wavelength range from 455 to 765 nm. A set of neural network based classifiers separates the pigmented malignant melanomas from the benign and dysplastic subgroups. A total of 110 lesions were used as the training set and 56 lesions were used as the testing set. This classifier performs with an overall 100% sensitivity and 92% specificity for the training set and 100% sensitivity and 88% specificity for the testing set. The second classifier was designed to separate the benign from the dysplastic subgroups. For the second classifier a total of 100 lesions were used as the training set and 51 lesions were used as the testing set. The overall classification rates were 94% and 88% for the training and testing sets respectively. 2010 Copyright SPIE - The International Society for Optical Engineering.

name of conference

  • Optical Diagnostics and Sensing X: Toward Point-of-Care Diagnostics

published proceedings


author list (cited authors)

  • Garcia-Uribe, A., Zou, J., Chang, T., Duvic, M., Prieto, V., & Wang, L. V.

citation count

  • 3

complete list of authors

  • Garcia-Uribe, Alejandro||Zou, Jun||Chang, Tzu-Hsuan||Duvic, Madeleine||Prieto, Victor||Wang, Lihong V

editor list (cited editors)

  • Coté, G. L.

publication date

  • February 2010