Survival of rough and smooth strains of Brucella abortus in bovine mammary gland macrophages. Academic Article

abstract

• Chronic bovine brucellosis is characterized by persistent infection of the mammary gland. The interaction of live Brucella abortus with bovine mammary gland macrophages was studied in vitro. Opsonization of smooth B abortus strain 2308 and rough strain 45/20 was required for phagocytosis by mammary gland macrophages. When opsonized with specific antiserum, strains 2308 and 45/20 stimulated a considerable oxidative burst when phagocytized by mammary gland macrophages. Intracellular survival rates for strain 2308 were significantly higher than those for strain 45/20. After being phagocytized, B abortus localized in phagosomes and phagolysosomes of mammary gland macrophages.

authors

• Adams, Leslie

published proceedings

• Am J Vet Res

author list (cited authors)

• Harmon, B. G., Adams, L. G., & Frey, M.

citation count

• 79

complete list of authors

• Harmon, BG||Adams, LG||Frey, M

publication date

• July 1988

published in

• American Journal of Veterinary Research  Journal

keywords

• Animals
• Brucella Abortus
• Cattle
• Female
• Macrophages
• Mammary Glands, Animal
• Microscopy, Electron
• Opsonin Proteins
• Phagocytosis
• Phagosomes
• Time Factors

PubMed Central ID

• 3138931

start page

• 1092

end page

• 1097

volume

• 49

issue

• 7