Molecular and Genetic Dissection of Plant Defense Response Against Microbial Pathogens
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abstract
During coevolution with pathogens, plants have developed sophisticated defense mechanisms to protect themselves against a wide range of microbial pathogens. We propose to investigate the complex network of signaling recognition and transduction during PAMP-triggered and effector-triggered immunity. Elucidating the functional interactions among poly(ADP-ribosyl)ation, DNA repair and plant immune responses will provide insights into disease control management mechanisms that can protect the genome from the damage induced by pathogens. Investigating the molecular mechanism of the plant-microbe interactions will facilitate understanding how plants perceive and respond to pathogens. The knowledge generated from these studies will help to dissect the defense responses at molecular and cellular level, which ultimately should lead to the development of novel and sustainable disease control strategies and improved crop production.
