Auxiliary-mediated site-specific peptide ubiquitylation. Academic Article uri icon

abstract

  • (Chemical Equation Presented) Lighting up ubiquitylation: A photolytically removable ligation auxiliary (Aux) was employed for the site-specific attachment of ubiquitin (Ub) to one of three lysine residues in a C-terminal peptide fragment of histone H2B (cH2B). Following photolysis, the ligation product was a viable substrate for the ubiquitin C-terminal hydrolase UCH-L3. 2007 Wiley-VCH Verlag GmbH & Co. KGaA.

published proceedings

  • Angew Chem Int Ed Engl

altmetric score

  • 6

author list (cited authors)

  • Chatterjee, C., McGinty, R. K., Pellois, J., & Muir, T. W.

citation count

  • 159

complete list of authors

  • Chatterjee, Champak||McGinty, Robert K||Pellois, Jean-Philippe||Muir, Tom W

publication date

  • April 2007

publisher