Cross spectra measure of neural signals and noise Conference Paper uri icon


  • Shannon's information rate formula does not work for wideband (aperiodic) signals with nonlinear transfer. The classical signal and noise measures used to characterize stochastic resonance do not work either because their way of distinguishing signal from noise fails. In a study published earlier, a new way of measuring and identifying noise and aperiodic (wideband) signals during strongly nonlinear transfer was introduced. The method was based on using cross-spectra between the input and the output. According to the study, in the case of linear transfer and sinusoidal signals, the method gives the same results as the classical method and in the case of aperiodic signals it gives a sensible measure. In this paper we refine the theory and present detailed simulations which validate and refine the conclusions reached in that study. The simulation results clearly confirm that the cross-spectral identifications of output signal and noise are sensible measures and we put the theory on a firm footing. As neural and ion channel signal transfer is nonlinear and aperiodic, the new method has direct applicability in biophysics and neural science.

name of conference

  • Fluctuations and Noise in Biological, Biophysical, and Biomedical Systems

published proceedings


author list (cited authors)

  • Sethuraman, S., & Kish, L. B.

citation count

  • 1

complete list of authors

  • Sethuraman, S||Kish, LB

editor list (cited editors)

  • Bezrukov, S. M., Frauenfelder, H., & Moss, F.

publication date

  • January 2003