Development of an optical polarimeter for in vivo glucose monitoring Conference Paper uri icon


  • In our investigation, we present both multi-spectral in vitro and preliminary single wavelength in vivo results supporting the use of optical polarimetry as a potential non-invasive method for glucose sensing. The site utilized for our in vivo measurements is the anterior chamber of the eye in a rabbit model. The anterior chamber of the eye contains a relatively clear and minimal scattering fluid known as the aqueous humor. The glucose levels of the aqueous humor are correlated to those of blood, therefore providing a mechanism to indirectly estimate blood glucose levels. A device to effectively couple light through the anterior chamber is also presented. As for the in vitro experiments, a multi-spectral approach is demonstrated as a method to minimize prediction error when glucose is not the only optically active component that varies in concentration.

name of conference

  • Optical Diagnostics of Biological Fluids IV

published proceedings


author list (cited authors)

  • Cameron, B. D., Gorde, H., & Cote, G. L.

citation count

  • 10

complete list of authors

  • Cameron, BD||Gorde, H||Cote, GL

editor list (cited editors)

  • Priezzhev, A. V., & Asakura, T.

publication date

  • January 1999