PARTURITION AND PREGNANCY OUTCOME IN RATS AS INFLUENCED BY MARGINAL INTAKE OF MAGNESIUM
Additional Document Info
Female Sprague-Dawley rats were fed 20% casein or 20% soy protein isolate diets which contained either adequate (800 mg/kg) or suboptimal (200 mg/kg) levels of magnesium from weaning through gestation. Reproductive performance was adversely affected by suboptimal magnesium levels and by consumption of soy protein. Number of implantation sites and number of live births were reduced in the low magnesium casein-based diet group. Neonatal mortality was highest in the low magnesium soy-based diet litters, perhaps because of additional nutrient deficiencies from use of soy protein. Intrauterine growth retardation occurred in both magnesium deficient groups. The length and difficulty of parturition and retention of conceptus in the postpartum uterus was increased for magnesium deficient groups. Nitrogen, fat, magnesium and zinc concentrations of pups were decreased in response to suboptimal magnesium intake. These effects were more pronounced than those which had been reported when a suboptimal magnesium level was fed only during breeding and/or gestation. 1983 Pergamon Press Ltd.