Bovine babesiosis: sterile immunity to Babesia bigemina and Babesia argentina infections. Academic Article

abstract

• Killed Babesia bigemina and Babesia argentina vaccine was prepared from the infected erythrocytes and from the infected plasma (AG-S) collected from acutely infected calves with bigemina and argentina. The vaccine was tested in Colombian cattle under field conditions in the Cauca Valley. A total of 40 calves two and one half months of age received killed-Babesia vaccine, and 5 calves were not vaccinated; they served as controls. Vaccinated and non-vaccinated control calves were exposed to field-borne challenge with Boophilus microplus infected ticks. On the basis of the data obtained in these experiments, it was found that a high degree of sterile immunity to Babesia bigemina and Babesia argentina can be produced in calves injected with killed-Babesia vaccine. It appears that sterile immunity plays an important role in the mechanism of acquired immunity to babesiosis other than the well-known co-infectious immunity known as premunition. 1974 E. & S. Livingstone.

authors

• Adams, Leslie

published proceedings

• Trop Anim Health Prod

author list (cited authors)

• Todorovic, R. A., Gonzalez, E. F., & Adams, L. G.

citation count

• 25

complete list of authors

• Todorovic, RA||Gonzalez, EF||Adams, LG

publication date

• November 1973

publisher

• Springer Nature  Publisher

keywords

• Anaplasmosis
• Animals
• Babesia
• Babesiosis
• Blood
• Body Weight
• Cattle
• Cattle Diseases
• Complement Fixation Tests
• Dermacentor
• Erythrocytes
• Freeze Drying
• Freund's Adjuvant
• Hematocrit
• Injections, Intramuscular
• Male
• Ticks
• Time Factors
• Vaccines

PubMed Central ID

• 4807692

Digital Object Identifier (DOI)

• 10.1007/BF02240424

start page

• 234

end page

• 245

volume

• 5

issue

• 4

URL

• http://dx.doi.org/10.1007/bf02240424

user-defined tag

• 3 Good Health and Well-Being