The chemotherapeutic efficacy of imidocarb dihydrochloride on concurrent bovine anaplasmosis and babesiosis. II. The effects of multiple treatments.
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Intact Anaplasma marginale, Babesia bigemina and Babesia argentina carrier calves treated intramuscularly five or ten times with 25 mg/kg of imidocarb dihydrochloride at 48 hour intervals, eliminated the Babesia infections but not Anaplasma infections. The parasitaemias became microscopically undemonstrable within 4 days following the first treatment and the packed cell volumes increased significantly within 18 days. Intoxications resulting in fatalities occurred in five of six calves given 10 intramuscular treatments of 25 mg/kg of imidocarb dihydrochloride at 48 hour intervals. 1974 E. & S. Livingstone Ltd.