DNA micelles as nanoreactors: efficient DNA functionalization with hydrophobic organic molecules. Academic Article

abstract

• We report a micelle-templated method to enhance the reactivity of DNA with highly hydrophobic molecules. Lipids, chromophores and polymers can be conjugated to DNA in high yield and under mild conditions. This method expands the range of DNA-templated reactions for DNA-encoded libraries, oligonucleotide and drug delivery, nanopore mimetics and DNA nanotechnology.

authors

• Bazzi, Hassan Said

published proceedings

• Chem Commun (Camb)

altmetric score

• 6.25

author list (cited authors)

• Trinh, T., Chidchob, P., Bazzi, H. S., & Sleiman, H. F.

citation count

• 30

complete list of authors

• Trinh, Tuan||Chidchob, Pongphak||Bazzi, Hassan S||Sleiman, Hanadi F

publication date

• September 2016

publisher

• Royal Society of Chemistry (RSC)  Publisher

published in

• Chemical Communications  Journal

keywords

• DNA
• Drug Carriers
• Hydrophobic And Hydrophilic Interactions
• Lipids
• Micelles
• Nanopores
• Nanotechnology
• Oligonucleotides
• Polymers
• Succinimides

PubMed Central ID

• 27533528

Digital Object Identifier (DOI)

• 10.1039/c6cc04970b

start page

• 10914

end page

• 10917

volume

• 52

issue

• 72

URL

• http%3A%2F%2Fdx.doi.org%2F10.1039%2Fc6cc04970b