DNA micelles as nanoreactors: efficient DNA functionalization with hydrophobic organic molecules Academic Article uri icon

abstract

  • We report a micelle-templated method to enhance the reactivity of DNA with highly hydrophobic molecules. Lipids, chromophores and polymers can be conjugated to DNA in high yield and under mild conditions. This method expands the range of DNA-templated reactions for DNA-encoded libraries, oligonucleotide and drug delivery, nanopore mimetics and DNA nanotechnology.

altmetric score

  • 6.25

author list (cited authors)

  • Trinh, T., Chidchob, P., Bazzi, H. S., & Sleiman, H. F.

citation count

  • 24

publication date

  • September 2016