Detection of integrins using surface enhanced Raman Spectroscopy Conference Paper uri icon


  • Integrins play an important role in the adhesion of cells to extracellular matrix and to other cells around them, more specifically fibronectin. The ultimate goal of this research is to detect these integrins on the surface of the cell with a combined atomic force microscopy (AFM) system coupled with a surface enhanced Raman spectroscopy (SERS) system. For this paper the focus was on identifying whether SERS is capable of being used to generate a unique spectrum for integrins. This was done using silver colloidal particles and the integrins 51 and V3. It was shown that a unique spectrum could be identified for each of these integrins at the nanomolar level.

name of conference

  • Optical Diagnostics and Sensing IV

published proceedings


author list (cited authors)

  • Gant, V. A., Chowdury, M. H., Meininger, G. A., & Cote, G. L.

citation count

  • 0

complete list of authors

  • Gant, VA||Chowdury, MH||Meininger, GA||Cote, GL

editor list (cited editors)

  • Cote, G. L., & Priezzhev, A. V.

publication date

  • June 2004