Prevalence of increased canine pancreas-specific lipase concentrations in young dogs with parvovirus enteritis. Academic Article uri icon


  • BACKGROUND: Pancreatic abnormalities during canine parvovirus (CPV) enteritis have not been studied prospectively. OBJECTIVES: The objective of this study was to evaluate the diagnostic significance of canine serum pancreas-specific lipase (Spec cPL) concentration in dogs with CPV enteritis for the presence of acute pancreatitis (AP). Puppies with naturally occurring CPV enteritis were recruited and prospectively allocated into 2 groups according to normal or increased serum Spec cPL concentration. Clinical signs, laboratory findings, and pancreas-associated variables were compared between groups, and the impact of possible AP on disease course, duration of hospitalization, and outcome was assessed. RESULTS: Serum Spec cPL concentration in 35 puppies was above the upper limit of the RI in 17/35 (48.6%) dogs (Group A) and within the RI in 18 dogs (Group B). An increased serum lipase activity was present in 29/35 (82.9%) dogs, and Group A dogs had a higher serum lipase activity than Group B (P = .006). Serum Spec cPL in Group A dogs was positively correlated with serum lipase activity at the day of presentation (r = .667; P = .003) and day of discharge (r = .628; P = .007). No statistically significant difference was found between groups (P = .233) for the presence of systemic inflammatory response syndrome (SIRS) (6/17 or 35.3% dogs Group A, and 8/18 or 44.4% dogs Group B), the disease course, duration of hospitalization, or outcome between groups. CONCLUSIONS: Increased serum Spec cPL is relatively common in dogs with CPV enteritis. However, such increases do not seem to correlate with the outcome of disease.

published proceedings

  • Vet Clin Pathol

altmetric score

  • 2.25

author list (cited authors)

  • Kalli, I. V., Adamama-Moraitou, K. K., Patsika, M. N., Pardali, D., Steiner, J. M., Suchodolski, J. S., ... Rallis, T. S.

citation count

  • 14

complete list of authors

  • Kalli, Irida V||Adamama-Moraitou, Katerina K||Patsika, Michael N||Pardali, Dimitra||Steiner, Jörg M||Suchodolski, Jan S||Menexes, George||Brellou, Georgia D||Rallis, Timoleon S

publication date

  • March 2017