Salivary gland malignancy with divergent differentiation: is it a teratocarcinosarcoma?

abstract

• Four poorly differentiated malignant lesions occurred in a 60-year-old Chinese male in the nasal cavity, submandibular gland, a lymph node in the neck, and the mandible. These malignant lesions developed within an 8-year period and each showed distinctive histological features. Among these malignant lesions, the neoplasm in the submandibular gland presented variegated histological and immunohistochemical (IHC) features and posed a diagnostic challenge in interpretation. Based on microscopic and IHC findings, we believe the diagnosis of teratocarcinosarcoma is justified for the submandibular neoplasm and the metastasis in the lymph node. The pathological features and diagnoses of these malignant lesions are discussed.

authors

• Cheng, Yi-Shing
• Wright, John

published proceedings

• Oral Surg Oral Med Oral Pathol Oral Radiol Endod

author list (cited authors)

• Cheng, Y., Kessler, H., Wright, J., Huang, E., Lin, J., Lin, L., & Chen, Y.

citation count

• 0

complete list of authors

• Cheng, Yi-Shing Lisa||Kessler, Harvey||Wright, John||Huang, Eric||Lin, Ju-Ru||Lin, Li-Min||Chen, Yuk-Kwan

publication date

• January 2007

publisher

• Elsevier  Publisher

published in

• Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology  Journal

keywords

• Carcinosarcoma
• Head And Neck Neoplasms
• Humans
• Lymph Nodes
• Male
• Mandibular Neoplasms
• Middle Aged
• Nasal Cavity
• Neoplasms, Multiple Primary
• Nose Neoplasms
• Submandibular Gland Neoplasms
• Teratocarcinoma

PubMed Central ID

• 17577548

Digital Object Identifier (DOI)

• 10.1016/j.tripleo.2006.06.062

start page

• 82

end page

• 88

volume

• 104

issue

• 1

URL

• http%3A%2F%2Fdx.doi.org%2F10.1016%2Fj.tripleo.2006.06.062