Salivary gland malignancy with divergent differentiation: is it a teratocarcinosarcoma? Academic Article uri icon


  • Four poorly differentiated malignant lesions occurred in a 60-year-old Chinese male in the nasal cavity, submandibular gland, a lymph node in the neck, and the mandible. These malignant lesions developed within an 8-year period and each showed distinctive histological features. Among these malignant lesions, the neoplasm in the submandibular gland presented variegated histological and immunohistochemical (IHC) features and posed a diagnostic challenge in interpretation. Based on microscopic and IHC findings, we believe the diagnosis of teratocarcinosarcoma is justified for the submandibular neoplasm and the metastasis in the lymph node. The pathological features and diagnoses of these malignant lesions are discussed.

published proceedings

  • Oral Surg Oral Med Oral Pathol Oral Radiol Endod

author list (cited authors)

  • Cheng, Y., Kessler, H., Wright, J., Huang, E., Lin, J., Lin, L., & Chen, Y.

citation count

  • 0

complete list of authors

  • Cheng, Yi-Shing Lisa||Kessler, Harvey||Wright, John||Huang, Eric||Lin, Ju-Ru||Lin, Li-Min||Chen, Yuk-Kwan

publication date

  • January 2007