Control in a family of Boolean networks
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abstract
Intervention in a gene regulatory network is used to avoid undesirable states, such as those associated with a disease. Several types of intervention have been studied in the framework of a probabilistic Boolean network (PBN), which is obtained by joining several Boolean networks (BN) using a probabilistic structure. In this work we treat a case in which we lack this governing probability structure for Boolean network selection, so we simply have a family of Boolean networks, where these networks possess a common attractor structure matching the data states, which are assumed to arise from sampling the steady state of the real biological network. 2006 IEEE.
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2006 IEEE International Workshop on Genomic Signal Processing and Statistics