A random signal model for cDNA microarrays Academic Article

abstract

• The images resulting from cDNA microarrays are highly random. There are many aspects to this randomness, including spot size, shape, intensity, uniformity, and circularity, as well as both foreground and background noise. This paper presents a random model for the generation of microarray images. The model is complicated and contains over twenty parameters. It can be used to test microarray imaging algorithms and to simulate the effects of various dependencies within the image formation process.

authors

• Dougherty, Edward

published proceedings

• MICROARRAYS: OPTICAL TECHNOLOGIES AND INFORMATICS

author list (cited authors)

• Balagurunathan, Y., Dougherty, E. R., Chen, Y. D., Bittner, M. L., & Trent, J. M.

citation count

• 0

complete list of authors

• Balagurunathan, Y||Dougherty, ER||Chen, YD||Bittner, ML||Trent, JM

editor list (cited editors)

• Bittner, M. L., Chen, Y., Dorsel, A. N., & Dougherty, E. R.

publication date

• June 2001

publisher

• SPIE, the international society for optics and photonics  Publisher

published in

• Proceedings of SPIE  Journal

keywords

• Cdna Spot Model
• Random Model
• Simulated Cdna Microarray

Digital Object Identifier (DOI)

• 10.1117/12.427985

start page

• 163

end page

• 170

volume

• 4266

URL

• http%3A%2F%2Fdx.doi.org%2F10.1117%2F12.427985