Coinfection with multiple strains of bovine papular stomatitis virus. Academic Article

abstract

• Bovine papular stomatitis virus (BPSV) infects cattle and, occupationally, humans. Prevalent subclinical infections, frequent reinfections, and virus persistence in healthy animals compound a poorly understood, but likely complex, scenario of BPSV perpetuation and transmission in nature. Here, we report the isolation of multiple BPSV strains coinfecting a single animal. Whole-genome analysis of isolated BPSV strains revealed genomic variability likely affecting virus virulence and infectivity. Further, incongruent phylogenetic relationships between viruses suggested genomic recombination. These results have significant implications for parapoxvirus infection biology and virus evolution in nature.

authors

• Edwards, John

published proceedings

• Arch Virol

altmetric score

• 0.25

author list (cited authors)

• Huang, T., Tulman, E. R., Diel, D. G., Khatiwada, S., Sims, W., Edwards, J. F., ... Delhon, G.

citation count

• 20

complete list of authors

• Huang, Tao||Tulman, Edan R||Diel, Diego G||Khatiwada, Sushil||Sims, Will||Edwards, John F||Wen, Xintian||Kutish, Gerald F||Rock, Daniel L||Delhon, Gustavo

publication date

• January 2015

publisher

• Springer Nature  Publisher

published in

• Archives of Virology  Journal

keywords

• Animals
• Base Sequence
• Cattle
• Cattle Diseases
• Coinfection
• Molecular Sequence Data
• Open Reading Frames
• Parapoxvirus
• Phylogeny
• Poxviridae Infections

Digital Object Identifier (DOI)

• 10.1007/s00705-015-2394-2

start page

• 1527

end page

• 1532

volume

• 160

issue

• 6

URL

• http%3A%2F%2Fdx.doi.org%2F10.1007%2Fs00705-015-2394-2