New ways to observe and control dynamics Conference Paper uri icon


  • We summarize recent progress aimed at observing biochemical and biological dynamics using confocal microscopy with 3D spatial resolution down to a few hundred nm and temporal resolution to 15 fs. We also review recent control of population dynamics using tailored ultrafast pulses, i.e. quantum control. Progress is described for i) feedback control, ii) multiphoton control, and iii) molecular pulse. Finally, using ultrafast light pulses, we combine confocal and quantum control techniques to produce a new way to measure the microscopic chemical environment, in this case pH, potentially with a spatial resolution of a few hundred nanometers.

name of conference

  • Laser Techniques for Condensed-Phase and Biological Systems

published proceedings


author list (cited authors)

  • Wilson, K. R., Bardeen, C., Barty, C., Brakenhoff, G. J., Buist, A. H., Cao, J. S., ... Yakovlev, V. V.

citation count

  • 1

complete list of authors

  • Wilson, KR||Bardeen, C||Barty, CPJ||Brakenhoff, GJ||Buist, AH||Cao, JS||Carpenter, SD||Che, JW||Fittinghoff, DN||Muller, M||Squier, JA||Warren, WS||Weber, PM||Yakovlev, VV

editor list (cited editors)

  • Scherer, N. F., & Hicks, J. M.

publication date

  • February 1998