CARS microscopy studies of collagen transformation Conference Paper uri icon


  • Nonlinear Raman spectroscopy is employed to study structural transformation of collagen (type I) in solution. Relatively strong signal and polarization background suppression reveal significant changes of the vibrational spectrum of collagen, which are attributed to the formation of cholesteric globules. Circular dichroism spectroscopy confirms the concentration dependent structural transformation. Excellent axial resolution achieved in nonlinear Raman microscopy also allows to study for the first time the effect of large molecule adhesion on the surface.

name of conference

  • Multiphoton Microscopy in the Biomedical Sciences V

published proceedings

  • Multiphoton Microscopy in the Biomedical Sciences V

author list (cited authors)

  • Petrov, G. I., Sona, L., Shcheslavskiy, V. I., & Yakovlev, V. V.

citation count

  • 0

complete list of authors

  • Petrov, GI||Sona, L||Shcheslavskiy, VI||Yakovlev, VV

editor list (cited editors)

  • Periasamy, A., & So, P.

publication date

  • March 2005