Nonlinear-optical photothermal modification of collagen Conference Paper

abstract

• We report on a novel mechanism of tissue modification. We demonstrate that if the train of ultrashort laser pulses has sufficient average power, multiphoton absorption can result in a significant heating of a localized area of a collagen-rich tissue leading to its photothermal modification. We propose a simple model describing the effect of local heating and derive a simple way of estimating the contribution of this mechanism for different parameters of incident radiation. Microscopic confocal imaging studies complement the spectroscopic studies to ensure the minimal destruction of surrounding areas of a tissue.

name of conference

• Laser Interaction with Tissue and Cells XV

authors

• Yakovlev, Vladislav

published proceedings

• LASER INTERACTION WITH TISSUE AND CELLS XV

author list (cited authors)

• Shcheslavskiy, V., Heathcote, R. D., & Yakovlev, V. V.

citation count

• 0

complete list of authors

• Shcheslavskiy, V||Heathcote, RD||Yakovlev, VV

editor list (cited editors)

• Jacques, S. L., & Roach, W. P.

publication date

• July 2004

publisher

• SPIE, the international society for optics and photonics  Publisher

published in

• Proceedings of SPIE  Journal

keywords

• Collagen
• Femtosecond
• Laser Surgery
• Microscopic Imaging
• Multiphoton
• Photothermal

Digital Object Identifier (DOI)

• 10.1117/12.531629

International Standard Book Number (ISBN) 10

• 0-8194-5227-0

start page

• 378

end page

• 384

volume

• 5319