Near-field optical imaging using optically trapped nanoparticles Conference Paper uri icon

abstract

  • Our ability to understand the structures and functions of living systems on a cellular and molecular level is mostly determined by the availability of imaging techniques capable of accessing a nanoscopic spatial resolution as well as providing structural information on molecular systems in vivo. While optical methods provide non-invasiveness, their spatial resolution is limited by a fundamental diffraction limit revealed more than 150 years ago by Ernst Abbe. This report addresses this grand-challenge and suggests a novel way of minimally invasive nanoscopic optical imaging inside a living cell. A powerful combination of optical tweezers, nonlinear optics and material science holds a promise of achieving unprecedented resolution of live-cell imaging, which should significantly advance our knowledge of molecular functions on a cellular level.

name of conference

  • Nanobiophotonics and Biomedical Applications II

published proceedings

  • NANOBIOPHOTONICS AND BIOMEDICAL APPLICATIONS II

author list (cited authors)

  • Faustov, A. R., Shcheslavskiy, V. I., Petrov, G. I., & Yakovlev, V. V.

citation count

  • 0

complete list of authors

  • Faustov, AR||Shcheslavskiy, VI||Petrov, GI||Yakovlev, VV

editor list (cited editors)

  • Cartwright, A. N., & Osinski, M.

publication date

  • April 2005