The application of laser-generated x-rays and time-gated imaging is best suited to problems that require both high resolution, large scatter reduction, and relatively long wavelength radiation (<40 keV), which can be easily detected by MCP devices. Two applications are currently under investigation: coronary angiography and high-resolution mammography. These experiments utilize a new 18-fs, 4-TW, 50-Hz repetition pump laser to produce x-ray fluxes comparable to the state-of-the-art rotating anode devices.