Mueller matrix imaging for cancer detection Conference Paper

abstract

• The Mueller matrix completely describes the optical polarization properties of a material. These properties are known to change with size of scatterers, birefringence, and number of scatterers. In cancerous and normal cells and tissues all of the above properties can change and therefore this approach can potentially be used to distinguish between noncancerous and cancerous tissues. In this paper, an Automated Mueller Matrix Polarization Imaging System (AMMPIS) is described that measures the Mueller matrix of a tissue sample. Mueller matrix images of normal, benign mole and cancerous lesions in Sinclair swine are presented along with a statistical analysis showing above 90% sensitivity and specificity for cancer detection with this approach.

name of conference

• Proceedings of the 25th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (IEEE Cat. No.03CH37439)

authors

• Cote, Gerard

published proceedings

• PROCEEDINGS OF THE 25TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, VOLS 1-4

author list (cited authors)

• Baldwin, A. M., Chung, J. R., Baba, J. S., Spiegelman, C. H., Amoss, M. S., & Cote, G. L.

citation count

• 11

complete list of authors

• Baldwin, AM||Chung, JR||Baba, JS||Spiegelman, CH||Amoss, MS||Cote, GL

publication date

• January 2003

publisher

• Institute of Electrical and Electronics Engineers (IEEE)  Publisher

published in

• 2015 37TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC)  Journal

keywords

• Backscattering
• Mueller Matrix
• Polarimetry
• Skin Cancer

Digital Object Identifier (DOI)

• 10.1109/IEMBS.2003.1279419

International Standard Book Number (ISBN) 10

• 0-7803-7789-3

URI

• https://hdl.handle.net/1969.1/340

start page

• 1027

end page

• 1030

volume

• 25

URL

• http%3A%2F%2Fdx.doi.org%2F10.1109%2Fiembs.2003.1279419