Probing the role of the bridging C509 between the [Fe4S4] cubane and the [Ni(p)Ni(d)] centre in the A-cluster of acetyl-coenzyme A synthase. Academic Article uri icon


  • The A-cluster of acetyl-coenzyme A synthase consists of an [Fe(4)S(4)] cubane bridged to a [Ni(p)Ni(d)] centre via C509 cysteinate. The bridging cysteinate, which could be substituted by histidine imidazole, mediates "communication" between the [Fe(4)S(4)] cubane and the [Ni(p)Ni(d)] centre during the synthesis of acetyl-coenzyme A.

published proceedings

  • Chem Commun (Camb)

author list (cited authors)

  • Liu, Y. i., Zhu, X., Wang, F., Ying, T., Li, P., Huang, Z., & Tan, X.

citation count

  • 5

complete list of authors

  • Liu, Yi||Zhu, Xiaofei||Wang, Feng||Ying, Tianlei||Li, Pingwei||Huang, Zhong-Xian||Tan, Xiangshi

publication date

  • January 2011