Basics in clinical nutrition: Protein and amino acid metabolism Academic Article uri icon


  • Proteins play a crucial role in biological processes and are continuously synthesized and broken down by different routes. On a whole body level, protein synthesis and breakdown are measured with the use of amino acid isotopes. Whole body protein synthesis and breakdown are each the net result of protein synthesis and breakdown in various organs. Although, in health, adults remain in zero protein balance, synthesis and breakdown are differentially affected by the stages of disease and prevailing conditions, e.g. starvation, feeding, sepsis, growth, convalescence, activity, etc., resulting in either net catabolism or anabolism. © 2008 European Society for Clinical Nutrition and Metabolism.

author list (cited authors)

  • Deutz, N.

citation count

  • 2

publication date

  • October 2008