Evidence for DNA loss as a determinant of genome size. Academic Article

abstract

• Eukaryotic genome sizes range over five orders of magnitude. This variation cannot be explained by differences in organismic complexity (the C value paradox). To test the hypothesis that some variation in genome size can be attributed to differences in the patterns of insertion and deletion (indel) mutations among organisms, this study examines the indel spectrum in Laupala crickets, which have a genome size 11 times larger than that of Drosophila. Consistent with the hypothesis, DNA loss is more than 40 times slower in Laupala than in Drosophila.

authors

• Johnston, J

published proceedings

• Science

altmetric score

• 3

author list (cited authors)

• Petrov, D. A., Sangster, T. A., Johnston, J. S., Hartl, D. L., & Shaw, K. L.

citation count

• 314

complete list of authors

• Petrov, DA||Sangster, TA||Johnston, JS||Hartl, DL||Shaw, KL

publication date

• February 2000

publisher

• American Association for the Advancement of Science (AAAS)  Publisher

published in

• Science  Journal

keywords

• Animals
• DNA
• Drosophila
• Evolution, Molecular
• Genome
• Gryllidae
• Likelihood Functions
• Multigene Family
• Mutation
• Phylogeny
• Polymerase Chain Reaction
• Pseudogenes
• Retroelements
• Sequence Deletion
• Species Specificity

PubMed Central ID

• 10669421

Digital Object Identifier (DOI)

• 10.1126/science.287.5455.1060

start page

• 1060

end page

• 1062

volume

• 287

issue

• 5455

URL

• http%3A%2F%2Fdx.doi.org%2F10.1126%2Fscience.287.5455.1060