Bioinformation and Omic Approaches for Characterization of Environmental Microorganisms
Chapter
Overview
Identity
Additional Document Info
Other
View All
Overview
abstract
2015 Elsevier Inc. All rights reserved. In biology, the term 'ome generally refers to the entirety or totality of a collection of things. In this chapter, we discuss the primary 'omics-based methods currently being used to characterize environmental microorganisms, and also approaches for analyzing and interpreting the bioinformation that these studies generate. Specifically, genomics, metagenomics, transcriptomics, proteomics and metabolomics are each discussed. Following this, we discuss "bioinformatics" utilized for marker-gene data including: the platforms used for sequence analysis; approaches to remove sequence error; and diversity and phylogenetic analyses. Subsequently, bioinformatics approaches for metagenomic data are described, including the layering of 'omics data using reference databases. Finally, correlation and network approaches to the analysis of metagenomic data are discussed.
