Microfluidic co-culture platform for CNS axon myelination Conference Paper uri icon

abstract

  • A microfluidic compartmentalized co-culture platform for central nervous system (CNS) axon myelination research has been developed. The platform is composed of two compartments connected via arrays of shallow microfluidic channels that function as fluidic and physical isolation barrier between the two compartments. Neurons from E 16-18 rats and oligodendrocytes (OLs) from P1-2 rats were cocultured inside the device and showed successful development into mature cells as well as isolation of neuronal cell bodies from axonal layer formed in the axon/glia compartment. 2008 CBMS.

published proceedings

  • 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference

author list (cited authors)

  • Park, J., Koito, H., Li, J., & Han, A.

complete list of authors

  • Park, J||Koito, H||Li, J||Han, A

publication date

  • January 2008