A cryo-cooling microfluidic channel device for a magnetic resonance (MR) microscopy system
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The development of a cryo-cooling microfluidic device for reducing the resistive noise of a magnetic resonance (MR) microcoil to improve its signal-to-noise ratio (SNR) in MR microscopy applications is presented. The radiofrequency (RF) spiral coil was cryo-cooled to liquid nitrogen temperature (-196C) by the integrated microfluidic channels carrying liquid nitrogen for decreasing the thermal noise of the coil. Our prototype had a Q factor increase of 1.78 folds while preventing the imaging sample from freezing.