SERKing Coreceptors for Receptors Academic Article uri icon


  • Plants have evolved a large number of cell surface-resident receptor-like kinases (RLKs) and receptor-like proteins (RLPs), many of which are implicated in sensing extrinsic and intrinsic signals, and govern diverse cellular responses. The signaling pathways mediated by RLKs and RLPs converge at a small group of RLKs, somatic embryogenesis receptor kinases (SERKs), via ligand-induced heterodimerization and transphosphorylation. As shared coreceptors in diverse signaling receptorsomes, SERKs exhibit functional plasticity yet maintain a high degree of signaling specificity. Here, we review recent advances in newly identified SERK functions in plant cell differentiation, growth, and immunity; discuss the regulation and activation mechanisms of SERK-associated receptorsomes; and provide insights into how SERKs maintain signaling specificity as convergent hubs in various signaling pathways.

altmetric score

  • 11.3

author list (cited authors)

  • Ma, X., Xu, G., He, P., & Shan, L.

citation count

  • 91

complete list of authors

  • Ma, Xiyu||Xu, Guangyuan||He, Ping||Shan, Libo

publication date

  • September 2016