Synergistic reaction of silver nitrate, silver nanoparticles, and methylene blue against bacteria. Academic Article

abstract

• In this paper we describe the antibacterial effect of methylene blue, MB, and silver nitrate reacting alone and in combination against five bacterial strains including Serratia marcescens and Escherichia coli bacteria. The data presented suggest that when the two components are combined and react together against bacteria, the effects can be up to three orders of magnitude greater than that of the sum of the two components reacting alone against bacteria. Analysis of the experimental data provides proof that a synergistic mechanism is operative within a dose range when the two components react together, and additive when reacting alone against bacteria.

authors

• Rentzepis, Peter

published proceedings

• Proc Natl Acad Sci U S A

altmetric score

• 0.75

author list (cited authors)

• Li, R., Chen, J., Cesario, T. C., Wang, X., Yuan, J. S., & Rentzepis, P. M.

citation count

• 38

complete list of authors

• Li, Runze||Chen, Jie||Cesario, Thomas C||Wang, Xin||Yuan, Joshua S||Rentzepis, Peter M

publication date

• November 2016

publisher

• Proceedings of the National Academy of Sciences  Publisher

published in

• Proceedings of the National Academy of Sciences of the United States of America  Journal

keywords

• Anti-Bacterial Agents
• Bacteria
• Dose-Response Relationship, Drug
• Drug Synergism
• Metal Nanoparticles
• Methylene Blue
• Microbial Sensitivity Tests
• Reactive Oxygen Species
• Silver
• Silver Ions
• Silver Nitrate
• Synergistic Effect

PubMed Central ID

• 27849602

Digital Object Identifier (DOI)

• 10.1073/pnas.1611193113

URI

• https://hdl.handle.net/1969.1/181163

start page

• 13612

end page

• 13617

volume

• 113

issue

• 48

URL

• http%3A%2F%2Fdx.doi.org%2F10.1073%2Fpnas.1611193113