A Buoyancy-Driven Compact Thermocycler for Rapid PCR Academic Article uri icon


  • We have designed a novel convective flow-based thermocycling system capable of performing high-speed DNA amplification via the polymerase chain reaction in a simplified and inexpensive format. Successful amplification of a 191 bp influenza-A target is demonstrated within 25 min using a 10 L reaction volume with no modification to standard laboratory protocols. The system is simple to assemble and can be readily integrated with existing laboratory instrumentation for automated operation. (JALA 2006;11:21721)

published proceedings


altmetric score

  • 3

author list (cited authors)

  • Agrawal, N., & Ugaz, V. M.

citation count

  • 7

complete list of authors

  • Agrawal, Nitin||Ugaz, Victor M

publication date

  • August 2006