PLOS Genetics Journal

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A loss-of-function mutation in RORB disrupts saltatorial locomotion in rabbits. 17:e1009429-e1009429. 2021
Chromosome number evolves at equal rates in holocentric and monocentric clades. 16:e1009076-e1009076. 2020
Mesenchyme-derived IGF2 is a major paracrine regulator of pancreatic growth and function. 16:e1009069-e1009069. 2020
The Mediator CDK8-Cyclin C complex modulates Dpp signaling in Drosophila by stimulating Mad-dependent transcription. 16:e1008832-e1008832. 2020
A new domestic cat genome assembly based on long sequence reads empowers feline genomic medicine and identifies a novel gene for dwarfism. 16:e1008926-e1008926. 2020
Integrative QTL analysis of gene expression and chromatin accessibility identifies multi-tissue patterns of genetic regulation. 16:e1008537-e1008537. 2020
Genome-wide discovery of the daily transcriptome, DNA regulatory elements and transcription factor occupancy in the monarch butterfly brain. 15:e1008265-e1008265. 2019
Developmental fidelity is imposed by genetically separable RalGEF activities that mediate opposing signals. 15:e1008056-e1008056. 2019
Gata4 regulates hedgehog signaling and Gata6 expression for outflow tract development. 15:e1007711-e1007711. 2019
Identification and validation of genetic variants predictive of gait in standardbred horses. 15:e1008146-e1008146. 2019
Genetics of adaptation in modern chicken. 15:e1007989-e1007989. 2019
Regulation of circadian clock transcriptional output by CLOCK:BMAL1. 14:e1007156-e1007156. 2018
Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. 13:e1007047-e1007047. 2017
Genomics-enabled analysis of the emergent disease cotton bacterial blight. 13:e1007003-e1007003. 2017
The evolution of Sex-linked barring alleles in chickens involves both regulatory and coding changes in CDKN2A. 13:e1006665-e1006665. 2017
Analysis of large versus small dogs reveals three genes on the canine X chromosome associated with body weight, muscling and back fat thickness. 13:e1006661-e1006661. 2017
CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis. 12:e1006415-e1006415. 2016
CLOCKWORK ORANGE Enhances PERIOD Mediated Rhythms in Transcriptional Repression by Antagonizing E-box Binding by CLOCK-CYCLE. 12:e1006430-e1006430. 2016
High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop. 12:e1006321-e1006321. 2016
Maize opaque10 Encodes a Cereal-Specific Protein That Is Essential for the Proper Distribution of Zeins in Endosperm Protein Bodies. 12:e1006270-e1006270. 2016
Correction: DNA Sequence Evolution and Rare Homoeologous Conversion in Tetraploid Cotton. 12:e1006206-e1006206. 2016
DNA Sequence Evolution and Rare Homoeologous Conversion in Tetraploid Cotton. 12:e1006012-e1006012. 2016
Sc65-Null Mice Provide Evidence for a Novel Endoplasmic Reticulum Complex Regulating Collagen Lysyl Hydroxylation. 12:e1006002-e1006002. 2016
Strong Selection at MHC in Mexicans since Admixture. 12:e1005847-e1005847. 2016
Escape from Lethal Bacterial Competition through Coupled Activation of Antibiotic Resistance and a Mobilized Subpopulation. 11:e1005722-e1005722. 2015
Retromer Is Essential for Autophagy-Dependent Plant Infection by the Rice Blast Fungus. 11:e1005704-e1005704. 2015
Trehalose Accumulation Triggers Autophagy during Plant Desiccation. 11:e1005705-e1005705. 2015
Leaderless Transcripts and Small Proteins Are Common Features of the Mycobacterial Translational Landscape. 11:e1005641-e1005641. 2015
The lncRNA RZE1 Controls Cryptococcal Morphological Transition. 11:e1005692-e1005692. 2015
Genome Wide Identification of SARS-CoV Susceptibility Loci Using the Collaborative Cross. 11:e1005504-e1005504. 2015
Multicopy Single-Stranded DNA Directs Intestinal Colonization of Enteric Pathogens. 11:e1005472-e1005472. 2015
Early Developmental and Evolutionary Origins of Gene Body DNA Methylation Patterns in Mammalian Placentas. 11:e1005442-e1005442. 2015
Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. 11:e1005405-e1005405. 2015
Genetic Regulation of Bone Metabolism in the Chicken: Similarities and Differences to Mammalian Systems. 11:e1005250-e1005250. 2015
β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates. 11:e1005208-e1005208. 2015
The UPR Branch IRE1-bZIP60 in Plants Plays an Essential Role in Viral Infection and Is Complementary to the Only UPR Pathway in Yeast. 11:e1005164-e1005164. 2015
Volatility of Mutator Phenotypes at Single Cell Resolution. 11:e1005151-e1005151. 2015
A Genomic Duplication is Associated with Ectopic Eomesodermin Expression in the Embryonic Chicken Comb and Two Duplex-comb Phenotypes. 11:e1004947-e1004947. 2015
Genetic Interaction Mapping Reveals a Role for the SWI/SNF Nucleosome Remodeler in Spliceosome Activation in Fission Yeast. 11:e1005074-e1005074. 2015
Reproductive Isolation of Hybrid Populations Driven by Genetic Incompatibilities. 11:e1005041-e1005041. 2015
Tfap2a Promotes Specification and Maturation of Neurons in the Inner Ear through Modulation of Bmp, Fgf and Notch Signaling. 11:e1005037-e1005037. 2015
A Multi-Megabase Copy Number Gain Causes Maternal Transmission Ratio Distortion on Mouse Chromosome 2. 11:e1004850-29. 2015
A Transposable Element within the Non-canonical Telomerase RNA of Arabidopsis thaliana Modulates Telomerase in Response to DNA Damage. 11:e1005281-e1005281. 2015
Aberrant Gene Expression in Humans. 11:e1004942-e1004942. 2015
Developmental Regulation of the Tetrahymena thermophila Origin Recognition Complex. 11:e1004875-e1004875. 2015
Protein Poly(ADP-ribosyl)ation Regulates Arabidopsis Immune Gene Expression and Defense Responses. 11:e1004936-e1004936. 2015
Enhanced Longevity by Ibuprofen, Conserved in Multiple Species, Occurs in Yeast through Inhibition of Tryptophan Import. 10:e1004860-e1004860. 2014
Copy Number Variation in the Horse Genome. 10:e1004712-e1004712. 2014
POT1a and Components of CST Engage Telomerase and Regulate Its Activity in Arabidopsis. 10:e1004738-e1004738. 2014
Signature Gene Expression Reveals Novel Clues to the Molecular Mechanisms of Dimorphic Transition in Penicillium marneffei. 10:e1004662-e1004662. 2014
A cis-Regulatory Mutation of PDSS2 Causes Silky-Feather in Chickens. 10:e1004576-e1004576. 2014
Phosphorylation of a Central Clock Transcription Factor Is Required for Thermal but Not Photic Entrainment. 10:e1004545-e1004545. 2014
Intrapopulation Genome Size Variation in D. melanogaster Reflects Life History Variation and Plasticity. 10:e1004522-e1004522. 2014
The Epidermal Growth Factor Receptor Critically Regulates Endometrial Function during Early Pregnancy. 10:e1004451-e1004451. 2014
Hyperactivated Wnt Signaling Induces Synthetic Lethal Interaction with Rb Inactivation by Elevating TORC1 Activities. 10:e1004357-e1004357. 2014
Worldwide Patterns of Ancestry, Divergence, and Admixture in Domesticated Cattle. 10:e1004254-e1004254. 2014
Complex Inheritance of Melanoma and Pigmentation of Coat and Skin in Grey Horses. 9:e1003248-e1003248. 2013
Comparative Genomic Analysis of the Endosymbionts of Herbivorous Insects Reveals Eco-Environmental Adaptations: Biotechnology Applications. 9:e1003131-e1003131. 2013
Genome-Wide Association Study Implicates Testis-Sperm Specific FKBP6 as a Susceptibility Locus for Impaired Acrosome Reaction in Stallions. 8:e1003139-e1003139. 2012
The Effective Population Size of Malaria Mosquitoes: Large Impact of Vector Control. 8:e1003097-e1003097. 2012
A Spatial and Temporal Gradient of Fgf Differentially Regulates Distinct Stages of Neural Development in the Zebrafish Inner Ear. 8:e1003068-e1003068. 2012
C. elegans Dopaminergic D2-Like Receptors Delimit Recurrent Cholinergic-Mediated Motor Programs during a Goal-Oriented Behavior. 8:e1003015-e1003015. 2012
Notch-Mediated Suppression of TSC2 Expression Regulates Cell Differentiation in the Drosophila Intestinal Stem Cell Lineage. 8:e1003045-e1003045. 2012
A Sexual Ornament in Chickens Is Affected by Pleiotropic Alleles at HAO1 and BMP2, Selected during Domestication. 8:e1002914-e1002914. 2012
Comparative Genomics of Plant-Associated Pseudomonas spp.: Insights into Diversity and Inheritance of Traits Involved in Multitrophic Interactions. 8:e1002784-e1002784. 2012
The Rose-comb Mutation in Chickens Constitutes a Structural Rearrangement Causing Both Altered Comb Morphology and Defective Sperm Motility. 8:e1002775-e1002775. 2012
A Systematic Analysis of Cell Cycle Regulators in Yeast Reveals That Most Factors Act Independently of Cell Size to Control Initiation of Division. 8:e1002590-e1002590. 2012
Inactivation of a Novel FGF23 Regulator, FAM20C, Leads to Hypophosphatemic Rickets in Mice. 8:e1002708-e1002708. 2012
A Complex Genomic Rearrangement Involving the Endothelin 3 Locus Causes Dermal Hyperpigmentation in the Chicken. 7:e1002412-e1002412. 2011
Transforming Growth Factor β Receptor Type 1 Is Essential for Female Reproductive Tract Integrity and Function. 7:e1002320-e1002320. 2011
Inactivation of Pmel Alters Melanosome Shape But Has Only a Subtle Effect on Visible Pigmentation. 7:e1002285-e1002285. 2011
Mutations in or near the Transmembrane Domain Alter PMEL Amyloid Formation from Functional to Pathogenic. 7:e1002286-e1002286. 2011
A Cholinergic-Regulated Circuit Coordinates the Maintenance and Bi-Stable States of a Sensory-Motor Behavior during Caenorhabditis elegans Male Copulation. 7:e1001326-e1001326. 2011
A Novel Unstable Duplication Upstream of HAS2 Predisposes to a Breed-Defining Skin Phenotype and a Periodic Fever Syndrome in Chinese Shar-Pei Dogs. 7:e1001332-e1001332. 2011
Population-Based Resequencing of Experimentally Evolved Populations Reveals the Genetic Basis of Body Size Variation in Drosophila melanogaster. 7:e1001336-e1001336. 2011
Lifespan Extension by Preserving Proliferative Homeostasis in Drosophila. 6:e1001159-15. 2010
Identification of Early Requirements for Preplacodal Ectoderm and Sensory Organ Development. 6:e1001133-e1001133. 2010
Correction: A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis. 6:10.1371/annotation/36fe7624-0904-46d4-a013-4b. 2010
Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN. 5:e1000747-e1000747. 2009
Molecular Decay of the Tooth Gene Enamelin (ENAM) Mirrors the Loss of Enamel in the Fossil Record of Placental Mammals. 5:e1000634-e1000634. 2009
A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis. 5:e1000590-e1000590. 2009
Copy Number Variation in Intron 1 of SOX5 Causes the Pea-comb Phenotype in Chickens. 5:e1000512-e1000512. 2009
Sensory Ataxic Neuropathy in Golden Retriever Dogs Is Caused by a Deletion in the Mitochondrial tRNATyr Gene. 5:e1000499-e1000499. 2009
The Complete Genome and Proteome of Laribacter hongkongensis Reveal Potential Mechanisms for Adaptations to Different Temperatures and Habitats. 5:e1000416-e1000416. 2009
Contrasting Mode of Evolution at a Coat Color Locus in Wild and Domestic Pigs. 5:e1000341-e1000341. 2009
Pervasive Hitchhiking at Coding and Regulatory Sites in Humans. 5:e1000336-e1000336. 2009
Diverse Splicing Patterns of Exonized Alu Elements in Human Tissues. 4:e1000225-e1000225. 2008
Sensory Perception of Food and Insulin-Like Signals Influence Seizure Susceptibility. 4:e1000117-e1000117. 2008
An Increase in Mitochondrial DNA Promotes Nuclear DNA Replication in Yeast. 4:e1000047-e1000047. 2008
Identification of the Yellow Skin Gene Reveals a Hybrid Origin of the Domestic Chicken. 4:e1000010-e1000010. 2008
Food Deprivation Attenuates Seizures through CaMKII and EAG K+ Channels. 3:e156-1632. 2007
Global Dissemination of a Single Mutation Conferring White Pericarp in Rice. 3:e133-1424. 2007
The Unconventional Xer Recombination Machinery of Streptococci/Lactococci. 3:e117-e117. 2007
A Role for the Adult Fat Body in Drosophila Male Courtship Behavior. 3:e16-0122. 2007
Functional Identification of Api5 as a Suppressor of E2F-Dependent Apoptosis In Vivo. 2:e196-1848. 2006
The Uncoupling Protein 1 Gene (UCP1) Is Disrupted in the Pig Lineage: A Genetic Explanation for Poor Thermoregulation in Piglets. 2:e129-1181. 2006
Novel Gene Acquisition on Carnivore Y Chromosomes. 2:e43-363. 2006
Novel Gene Acquisition on Carnivore Y Chromosomes. preprint:e43-e43. 2005
Identification of the Yellow Skin Gene Reveals a Hybrid Origin of the Domestic Chicken. preprint:e10-e10. 2005