Acute exercise and training alter blood lipid and lipoprotein profiles differently in overweight and obese men and women.
Academic Article
Overview
Research
Identity
Additional Document Info
Other
View All
Overview
abstract
Our purpose was to elucidate effects of acute exercise and training on blood lipids-lipoproteins, and high-sensitivity C-reactive protein (hsCRP) in overweight/obese men (n = 10) and women (n = 8); age, BMI, body fat percentage, and VO(2)max were (mean SEM): 45 2.5 years, 31.9 1.4 kgm(-2), 41.1 1.5%, and 25.2 1.3 mlO(2)kg(-1)min(-1). Before exercise training subjects performed an acute exercise session on a treadmill (70% VO(2)max, 400 kcal energy expenditure), followed by 12 weeks of endurance exercise training (land-based or aquatic-based treadmill): 3 sessionsweek(-1), progressing to 500 kcalsession(-1) during which subjects maintained accustomed dietary habits. After training, the acute exercise session was repeated. Blood samples, obtained immediately before and 24 h after acute exercise sessions, were analyzed for serum lipids, lipoproteins, and hsCRP adjusted for plasma volume shifts. Exercise training increased VO(2)max (+3.67 mlO(2)kg(-1)min(-1), P < 0.001) and reduced body weight (-2.7 kg, P < 0.01). Training increased high-density lipoprotein (HDL) and HDL(2b)-cholesterol (HDL-C) concentrations (+3.7 and +2.4 mgdl(-1), P < 0.05) and particle numbers (+588 and +206 nmoll(-1), P < 0.05) in men. In women despite no change in total HDL-C, subfractions shifted from HDL(3)-C (-3.2, P < 0.01) to HDL(2b)-C (+3.5, P < 0.05) and HDL(2a)-C (+2.2 mgdl(-1), P < 0.05), with increased HDL(2b) particle number (+313 nmoll(-1), P < 0.05). Training reduced LDL(3) concentration and particle number in women (-1.6 mgdl(-1) and -16 nmoll(-1), P < 0.05). Acute exercise reduced the total cholesterol (TC): HDL-C ratio in men (-0.16, P < 0.01) and increased hsCRP in all subjects (+0.05 mgdl(-1), P < 0.05), regardless of training. Training did not affect acute exercise responses. Our data support the efficacy of endurance training, without dietary intervention, to elicit beneficial changes in blood lipids-lipoproteins in obese men and women.