Chromosomal assignments for the equine AMPK family genes Academic Article

abstract

• 5′-AMP-activated protein kinase (AMPK), comprised of a catalytic α-subunit and non-catalytic β- and γ-subunits, plays a pivotal role in the regulation of cellular energy homeostasis. 1The PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2 and PRKAG3 genes encode the seven possible subunits of a functional mammalian AMPK heterotrimer. We derived over 70% of the coding sequence of each equine AMPK subunit gene and determined their chromosomal locations by radiation hybrid mapping and fluorescence in situ hybridization (FISH). © 2006 International Society for Animal Genetics.

authors

• Raudsepp, Terje

author list (cited authors)

• Dranchak, P. K., Ekenstedt, K. J., Valberg, S. J., Chowdhary, B. P., Raudsepp, T., & Mickelson, J. R.

citation count

• 4

complete list of authors

• Dranchak, PK||Ekenstedt, KJ||Valberg, SJ||Chowdhary, BP||Raudsepp, T||Mickelson, JR

publication date

• March 2006

publisher

• Wiley  Publisher

published in

• ANIMAL GENETICS  Journal

keywords

• AMP-Activated Protein Kinases
• Animals
• Chromosomes, Mammalian
• Horses
• In Situ Hybridization, Fluorescence
• Lod Score
• Multienzyme Complexes
• Multigene Family
• Protein-Serine-Threonine Kinases
• Radiation Hybrid Mapping
• Sequence Analysis, DNA

PubMed Central ID

• 16734697

Digital Object Identifier (DOI)

• 10.1111/j.1365-2052.2006.01431.x

start page

• 293

end page

• 294

volume

• 37

issue

• 3