Chromosomal assignments for the equine AMPK family genes. Academic Article

abstract

• 5-AMP-activated protein kinase (AMPK), comprised of a catalytic -subunit and non-catalytic - and -subunits, plays a pivotal role in the regulation of cellular energy homeostasis. 1The PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2 and PRKAG3 genes encode the seven possible subunits of a functional mammalian AMPK heterotrimer. We derived over 70% of the coding sequence of each equine AMPK subunit gene and determined their chromosomal locations by radiation hybrid mapping and fluorescence in situ hybridization (FISH). 2006 International Society for Animal Genetics.

authors

• Raudsepp, Terje

published proceedings

• Anim Genet

author list (cited authors)

• Dranchak, P. K., Ekenstedt, K. J., Valberg, S. J., Chowdhary, B. P., Raudsepp, T., & Mickelson, J. R.

citation count

• 4

complete list of authors

• Dranchak, PK||Ekenstedt, KJ||Valberg, SJ||Chowdhary, BP||Raudsepp, T||Mickelson, JR

publication date

• June 2006

publisher

• Wiley  Publisher

published in

• Animal Genetics  Journal

keywords

• AMP-Activated Protein Kinases
• Animals
• Chromosomes, Mammalian
• Horses
• In Situ Hybridization, Fluorescence
• Lod Score
• Multienzyme Complexes
• Multigene Family
• Protein-Serine-Threonine Kinases
• Radiation Hybrid Mapping
• Sequence Analysis, DNA

PubMed Central ID

• 16734697

Digital Object Identifier (DOI)

• 10.1111/j.1365-2052.2006.01431.x

start page

• 293

end page

• 294

volume

• 37

issue

• 3