Chromosomal assignments for the equine AMPK family genes Academic Article uri icon

abstract

  • 5′-AMP-activated protein kinase (AMPK), comprised of a catalytic α-subunit and non-catalytic β- and γ-subunits, plays a pivotal role in the regulation of cellular energy homeostasis. 1The PRKAA1, PRKAA2, PRKAB1, PRKAB2, PRKAG1, PRKAG2 and PRKAG3 genes encode the seven possible subunits of a functional mammalian AMPK heterotrimer. We derived over 70% of the coding sequence of each equine AMPK subunit gene and determined their chromosomal locations by radiation hybrid mapping and fluorescence in situ hybridization (FISH). © 2006 International Society for Animal Genetics.

author list (cited authors)

  • Dranchak, P. K., Ekenstedt, K. J., Valberg, S. J., Chowdhary, B. P., Raudsepp, T., & Mickelson, J. R.

citation count

  • 4

complete list of authors

  • Dranchak, PK||Ekenstedt, KJ||Valberg, SJ||Chowdhary, BP||Raudsepp, T||Mickelson, JR

publication date

  • March 2006

publisher