Bioactive silicate nanoplatelets for osteogenic differentiation of human mesenchymal stem cells. Academic Article

abstract

• Novel silicate nanoplatelets that induce osteogenic differentiation of human mesenchymal stem cells (hMSCs) in the absence of any osteoinductive factor are reported. The presence of the silicate triggers a set of events that follows the temporal pattern of osteogenic differentiation. These findings underscore the potential applications of these silicate nanoplatelets in designing bioactive scaffolds for musculoskeletal tissue engineering.

authors

• Gaharwar, Akhilesh

published proceedings

• Adv Mater

altmetric score

• 51.166

author list (cited authors)

• Gaharwar, A. K., Mihaila, S. M., Swami, A., Patel, A., Sant, S., Reis, R. L., ... Khademhosseini, A.

citation count

• 389

complete list of authors

• Gaharwar, Akhilesh K||Mihaila, Silvia M||Swami, Archana||Patel, Alpesh||Sant, Shilpa||Reis, Rui L||Marques, Alexandra P||Gomes, Manuela E||Khademhosseini, Ali

publication date

• June 2013

publisher

• Wiley  Publisher

published in

• ADVANCED MATERIALS  Journal

keywords

• Cell Differentiation
• Cell Survival
• Cells, Cultured
• Humans
• Mesenchymal Stem Cells
• Nanostructures
• Osteogenesis
• Reactive Nitrogen Species
• Reactive Oxygen Species
• Silicates
• Tissue Engineering

PubMed Central ID

• 23670944

Digital Object Identifier (DOI)

• 10.1002/adma.201300584

start page

• 3329

end page

• 3336

volume

• 25

issue

• 24

URL

• http%3A%2F%2Fdx.doi.org%2F10.1002%2Fadma.201300584