3D Biomaterial Microarrays for Regenerative Medicine: Current State-of-the-Art, Emerging Directions and Future Trends. Academic Article

abstract

• Three dimensional (3D) biomaterial microarrays hold enormous promise for regenerative medicine because of their ability to accelerate the design and fabrication of biomimetic materials. Such tissue-like biomaterials can provide an appropriate microenvironment for stimulating and controlling stem cell differentiation into tissue-specific lineages. The use of 3D biomaterial microarrays can, if optimized correctly, result in a more than 1000-fold reduction in biomaterials and cells consumption when engineering optimal materials combinations, which makes these miniaturized systems very attractive for tissue engineering and drug screening applications.

authors

• Gaharwar, Akhilesh

published proceedings

• Adv Mater

altmetric score

• 4.2

author list (cited authors)

• Gaharwar, A. K., Arpanaei, A., Andresen, T. L., & Dolatshahi-Pirouz, A.

citation count

• 76

complete list of authors

• Gaharwar, Akhilesh K||Arpanaei, Ayyoob||Andresen, Thomas L||Dolatshahi-Pirouz, Alireza

publication date

• January 2016

publisher

• Wiley  Publisher

published in

• ADVANCED MATERIALS  Journal

keywords

• 3d Microarrays
• 3d Printing
• Biomaterials
• Biomimetic Materials
• Cell Differentiation
• Cell Survival
• Embryonic Stem Cells
• Extracellular Matrix Proteins
• High-Throughput Screening Assays
• Humans
• Microarray Analysis
• Microfabrication
• Regenerative Medicine
• Small Molecule Libraries
• Tissue Engineering
• Tissue Scaffolds

PubMed Central ID

• 26607415

Digital Object Identifier (DOI)

• 10.1002/adma.201503918

start page

• 771

end page

• 781

volume

• 28

issue

• 4

URL

• http%3A%2F%2Fdx.doi.org%2F10.1002%2Fadma.201503918