Glycosylated chicken growth hormone. Academic Article uri icon

abstract

  • In an attempt to raise monoclonal antibodies to chicken pituitary glycoprotein hormones, mice were immunized with the concanavalin A-adsorbed components of a hypophyseal extract. Fusions of these spleen cells with myeloma cells repeatedly yielded hybridoma lines secreting antibodies that recognized specifically the pituitary caudal acidophils, known as the somatotropes. This paper reveals the existence of a glycosylated counterpart of the well-established holoprotein form of chicken growth hormone, similar to what has been established for human growth hormone and prolactin.

published proceedings

  • Gen Comp Endocrinol

author list (cited authors)

  • Berghman, L. R., Lens, P., Decuypere, E., Kühn, E. R., & Vandesande, F
  • Berghman, L. R., Lens, P., Decuypere, E., Kühn, E. R., & Vandesande, F.

citation count

  • 44

complete list of authors

  • Berghman, LR||Lens, P||Decuypere, E||Kühn, ER||Vandesande, F

publication date

  • December 1987