Ontogeny of type I and type III deiodinase activities in embryonic and posthatch chicks: relationship with changes in plasma triiodothyronine and growth hormone levels. Academic Article uri icon


  • 1. The ontogeny of type I and type III deiodinase activities was studied in embryonic and posthatch chicks. 2. Hepatic type I activity showed a 3-fold increase up to the period of pipping and hatching and decreased slowly thereafter. 3. Hepatic type III activity increased by 3-fold from E14 to E17 and decreased more than 10-fold from E17 to C0. Posthatch levels were very low. 4. Type I activity in the kidney decreased slowly after hatching while type III activity was very low over the whole period studied. 5. Developmental changes during the late embryonic period suggest a causal relationship between the increase in plasma GH and T3 levels and the decrease in hepatic type III activity.

published proceedings

  • Comp Biochem Physiol Comp Physiol

author list (cited authors)

  • Darras, V. M., Visser, T. J., Berghman, L. R., & Khn, E. R.

citation count

  • 150

complete list of authors

  • Darras, VM||Visser, TJ||Berghman, LR||Kühn, ER

publication date

  • September 1992