Determining the inhibition constants in the HCH-1 model of cellulose hydrolysis. Academic Article uri icon


  • The products of cellulose hydrolysis, glucose and cellobiose, caused noncompetitive inhibition patterns to be exhibited when Thermomonospora sp. YX cellulase hydrolyzed dyed cellulose. The glucose binding constant, beta(1), was 0.00683 +/- 0.00031 L/g and the cellobiose binding constant, beta(2), was 0.095 +/- 0.0058 L/g. Thus, cellobiose was about 14 times more inhibitory than glucose.

published proceedings

  • Biotechnol Bioeng

author list (cited authors)

  • Holtzapple, M. T., Caram, H. S., & Humphrey, A. E.

citation count

  • 42

complete list of authors

  • Holtzapple, MT||Caram, HS||Humphrey, AE

publication date

  • July 1984