Type I conceptus interferons: maternal recognition of pregnancy signals and potential therapeutic agents. Academic Article

abstract

• In summary, Type I conceptus interferons of sheep, cows, and goats (perhaps all ruminants), which signal maternal recognition of pregnancy, may be useful for enhancing fertility in animal agriculture and may have a role in human and veterinary medicine as well. The Type I conceptus interferons share antiviral, anticellular, and immunosuppressive properties with Type I leukocyte interferons, but lack their cytotoxic effects, which may make them especially useful as therapeutic agents in human and veterinary medicine. The unique N-terminal structure of oTP-1 may account for its distinctive biological properties, including its antiluteolytic activity.

authors

• Bazer, Fuller

published proceedings

• Am J Reprod Immunol

altmetric score

• 3

author list (cited authors)

• Bazer, F. W., & Johnson, H. M.

citation count

• 34

complete list of authors

• Bazer, FW||Johnson, HM

publication date

• August 1991

publisher

• Wiley  Publisher

published in

• American Journal of Reproductive Immunology  Journal

keywords

• Animals
• Female
• Humans
• Interferon Type I
• Pregnancy
• Pregnancy Proteins
• Pregnancy, Animal

PubMed Central ID

• 1741934

Digital Object Identifier (DOI)

• 10.1111/j.1600-0897.1991.tb00696.x

start page

• 19

end page

• 22

volume

• 26

issue

• 1

URL

• http://dx.doi.org/10.1111/j.1600-0897.1991.tb00696.x

user-defined tag

• 3 Good Health and Well-Being