Electrospinning of silica nanochannels for single molecule detection Academic Article

abstract

• We have fabricated silica nanochannels with inner diameter as small as 20 nm using a scanned coaxial electrospinning and demonstrated their application for single molecule detection. A coaxial jet, with the use of motor oil as the core and silica sol-gel solution as the shell, is extruded through a coaxial source and deposited on the rotating collector as oriented nanofibers. They are then annealed to cross-link silica and eliminate motor oil, thereby forming nanochannels. Subsequently, a fluorescent dye was injected into the individual nanochannels via a capillary force and single molecule detection was performed by monitoring the photon signals from 5-Iodoacetamidofluorescein. 2006 American Institute of Physics.

authors

• Chang, Kuang-An
• Kameoka, Jun

published proceedings

• APPLIED PHYSICS LETTERS

author list (cited authors)

• Wang, M., Jing, N., Su, C. B., Kameoka, J., Chou, C. K., Hung, M. C., & Chang, K. A.

citation count

• 62

complete list of authors

• Wang, M||Jing, N||Su, CB||Kameoka, J||Chou, CK||Hung, MC||Chang, KA

publication date

• January 2006

publisher

• AIP Publishing  Publisher

published in

• Applied Physics Letters  Journal

keywords

• Bioengineering
• Nanotechnology

Digital Object Identifier (DOI)

• 10.1063/1.2165277

start page

• 033106

end page

• 033106

volume

• 88

issue

• 3

URL

• http%3A%2F%2Fdx.doi.org%2F10.1063%2F1.2165277