Three-Dimensional Flexible Electronics Enabled by Shape Memory Polymer Substrates for Responsive Neural Interfaces. Academic Article

abstract

• Planar electronics processing methods have enabled neural interfaces to become more precise and deliver more information. However, this processing paradigm is inherently 2D and rigid. The resulting mechanical and geometrical mismatch at the biotic-abiotic interface can elicit an immune response that prevents effective stimulation. In this work, a thiol-ene/acrylate shape memory polymer is utilized to create 3D softening substrates for stimulation electrodes. This substrate system is shown to soften in vivo from more than 600 to 6 MPa. A nerve cuff electrode that coils around the vagus nerve in a rat and that drives neural activity is demonstrated.

authors

• Maitland, Duncan
• Ware, Taylor

published proceedings

• Macromol Mater Eng

altmetric score

• 12.5

author list (cited authors)

• Ware, T., Simon, D., Hearon, K., Liu, C., Shah, S., Reeder, J., ... Voit, W. E.

citation count

• 103

complete list of authors

• Ware, Taylor||Simon, Dustin||Hearon, Keith||Liu, Clive||Shah, Sagar||Reeder, Jonathan||Khodaparast, Navid||Kilgard, Michael P||Maitland, Duncan J||Rennaker, Robert L||Voit, Walter E

publication date

• December 2012

publisher

• Wiley  Publisher

published in

• Macromolecular Materials and Engineering  Journal

keywords

• Flexible Electronics
• Neural Interfaces
• Shape Memory Polymers
• Stimuli-sensitive Polymers
• THERMOSETS

PubMed Central ID

• 25530708

Digital Object Identifier (DOI)

• 10.1002/mame.201200241

start page

• 1193

end page

• 1202

volume

• 297

issue

• 12

URL

• http%3A%2F%2Fdx.doi.org%2F10.1002%2Fmame.201200241