Using micro and nanofluidics with surface enhanced Raman spectroscopy for in vitro blood based biomarker detection Conference Paper

abstract

• In this presentation we will discuss the development of a point-of-care optofluidic device that uses gold nanoparticlebased surface enhanced Raman spectroscopy (SERS) for detection of blood biomarkers. SERS approaches have been successfully used for detection of analytes due to the large enhancements provided by the interaction between the light, gold particles, and analyte. However, SERS approaches developed for use to accurately quantify an analyte have suffered from a lack of repeatability. We will describe our SERS optofluidic device with functionalized nanoparticles that helps to overcome these problems and will show results with a focus on blood cardiac biomarkers. 2014 SPIE.

name of conference

• Translational Biophotonics

authors

• Cote, Gerard
• Kameoka, Jun

published proceedings

• TRANSLATIONAL BIOPHOTONICS

author list (cited authors)

• Cote, G. L., Kameoka, J., & Marks, H.

citation count

• 0

complete list of authors

• Cote, Gerard L||Kameoka, Jun||Marks, Haley

editor list (cited editors)

• Tkaczyk, T. S.

publication date

• January 2014

publisher

• SPIE, the international society for optics and photonics  Publisher

published in

• Proceedings of SPIE  Journal

keywords

• Blood Biomarkers
• Nanoparticles
• Optofluidic
• Point-of-care
• Surface Enhanced Raman Spectroscopy

Digital Object Identifier (DOI)

• 10.1117/12.2065418

International Standard Book Number (ISBN) 13

• 9780819496263

start page

• 91550e-91550e-5

volume

• 9155

URL

• http%3A%2F%2Fdx.doi.org%2F10.1117%2F12.2065418