Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism.
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Gohil, V. M., Zhu, L., Baker, C. D., Cracan, V., Yaseen, A., Jain, M., ... Mootha, V. K.
complete list of authors
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Gohil, Vishal M||Zhu, Lin||Baker, Charli D||Cracan, Valentin||Yaseen, Abbas||Jain, Mohit||Clish, Clary B||Brookes, Paul S||Bakovic, Marica||Mootha, Vamsi K
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keywords
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Animals
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Antiemetics
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Cell Line
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Cell Respiration
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Cytosol
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Energy Metabolism
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Enzyme Inhibitors
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Ethanolamines
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Gene Knockdown Techniques
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Humans
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Meclizine
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Metabolic Networks And Pathways
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Metabolomics
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Mice
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Mitochondria
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Phosphatidylethanolamine
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Phosphoethanolamine
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RNA Nucleotidyltransferases
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Respiration
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