Magnetic resonance flow velocity and temperature mapping of a shape memory polymer foam device. Academic Article uri icon

abstract

  • BACKGROUND: Interventional medical devices based on thermally responsive shape memory polymer (SMP) are under development to treat stroke victims. The goals of these catheter-delivered devices include re-establishing blood flow in occluded arteries and preventing aneurysm rupture. Because these devices alter the hemodynamics and dissipate thermal energy during the therapeutic procedure, a first step in the device development process is to investigate fluid velocity and temperature changes following device deployment. METHODS: A laser-heated SMP foam device was deployed in a simplified in vitro vascular model. Magnetic resonance imaging (MRI) techniques were used to assess the fluid dynamics and thermal changes associated with device deployment. RESULTS: Spatial maps of the steady-state fluid velocity and temperature change inside and outside the laser-heated SMP foam device were acquired. CONCLUSIONS: Though non-physiological conditions were used in this initial study, the utility of MRI in the development of a thermally-activated SMP foam device has been demonstrated.

published proceedings

  • Biomed Eng Online

author list (cited authors)

  • Small, W., Gjersing, E., Herberg, J. L., Wilson, T. S., & Maitland, D. J.

citation count

  • 13

complete list of authors

  • Small, Ward||Gjersing, Erica||Herberg, Julie L||Wilson, Thomas S||Maitland, Duncan J

publication date

  • December 2009