Multicentric Benign Epithelial Inclusions in a Free-ranging Risso's Dolphin (Grampus griseus). Academic Article uri icon


  • This report describes the histological and immunohistochemical features of multicentric, benign, epithelial inclusions (BEIs) in a free-ranging, adult, female Risso's dolphin (Grampus griseus). The differential diagnoses included ectopic hamartomatous epithelial inclusions, non-Mllerian choristoma, Mllerian choristoma and low-grade metastatic carcinoma/mesothelioma. The most likely diagnosis of such BEIs was multicentric, embolic, reactive mesothelium, as suggested by cytomorphological and immunophenotypical features of the BEIs, the occurrence of focal pleural rupture and the immunophenotype of the pleural mesothelium. The former represents a pathological condition not previously reported in a marine mammal species, rarely described in animals, and relatively infrequently recognized in man.

published proceedings

  • J Comp Pathol

altmetric score

  • 0.5

author list (cited authors)

  • Diaz-Delgado, J., Quesada-Canales, O., Arbelo, M., Sierra, E., Edwards, J. F., Suarez-Bonnet, A., ... Fernandez, A.

citation count

  • 4

complete list of authors

  • Diaz-Delgado, J||Quesada-Canales, O||Arbelo, M||Sierra, E||Edwards, JF||Suarez-Bonnet, A||Santana-Suarez, C||Espinosa de Los Monteros, A||Fernandez, A

publication date

  • August 2016