Detection of picomolar concentrations of lead in water using albumin-based fluorescence sensor. Academic Article uri icon


  • Comprehensive analysis of fluorescence of albumin shows a weak fluorescence band at 430 nm, whose intensity exhibits a remarkable sensitivity to the presence of heavy ions in water. Using this fluorescence as a marker, as low as 10 pM concentration of lead can be routinely detected. Such a great sensitivity is explained in terms of electrostatic interactions in solution, which promote protein agglomeration. The latter is independently confirmed using dynamic light scattering measurements.

published proceedings

  • Appl Phys Lett

author list (cited authors)

  • Saha, A., & Yakovlev, V. V.

citation count

  • 7

complete list of authors

  • Saha, Anushree||Yakovlev, Vladislav V

publication date

  • October 2009