The release of soluble vasoactive material from Trypanosoma congolense in intraperitoneal diffusion chambers. Academic Article

abstract

• Millipore diffusion chambers containing living or lysed Trypanosoma congolense cause a local inflammatory reaction when implanted intraperitoneally into rats. Empty chambers do not do this. The active material is of low molecular weight and is possibly peptide in nature. It appears to act by increasing local vascular permeability. It was found to be neither chemotactic nor cytotoxic in several assay systems. It is considered that this material may contribute to the pathogenesis of T. congolense infection in animals.

authors

• Tizard, Ian

published proceedings

• Trans R Soc Trop Med Hyg

author list (cited authors)

• Tizard, I. R., & Holmes, W. L.

citation count

• 6

complete list of authors

• Tizard, IR||Holmes, WL

publication date

• January 1977

publisher

• Oxford University Press (OUP)  Publisher

published in

• Transactions of The Royal Society of Tropical Medicine and Hygiene  Journal

keywords

• Animals
• Capillary Permeability
• Diffusion
• Female
• Granulation Tissue
• Peritoneal Cavity
• Peritonitis
• Rats
• Trypanosoma

PubMed Central ID

• 860314

Digital Object Identifier (DOI)

• 10.1016/0035-9203(77)90208-5

start page

• 52

end page

• 55

volume

• 71

issue

• 1

URL

• http://dx.doi.org/10.1016/0035-9203(77)90208-5